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The Science
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Science, slowed down. Formulas, finely tuned. Skin, finally understood.
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Puriste was designed with one belief: when skincare is precise, the skin responds.
Developed by dermatologist Dr. Sylvia Garnis-Jones, our signature cream is powered by CAG-pH4™, an unbuffered glycolic complex delivered at a pH of 4.0—clinically shown to stimulate collagen production and speed up cellular renewal without irritation.
Balanced by the Single-Dose Barrier System™ and Irritant-Free Chemistry™, the formula uses biomimetic lipids—like jojoba, olive, and shea—to protect the barrier while actives get to work.
One dose. One step. Real science, finally simplified.

The One-Step Skin Rebuilder
The Single-Dose Barrier System™
Inspired by how dermatologists prescribe topicals, this system delivers a single, calibrated dose—once nightly. It pairs barrier-repairing lipids with biomimetic emollients like shea butter, jojoba, and olive oil to replenish the skin’s lipid matrix while actives get to work. No layering. No overstimulation. Just precision delivery designed to support skin renewal without compromising its structure.

The Cellular Refiner
CAG-pH4™ Glycolic Complex
At the heart of our core formula is CAG-pH4™, our proprietary, unbuffered glycolic compound delivered at a precise pH of 4.0. This is the pH range clinically shown to stimulate fibroblast activity—encouraging collagen production, cell turnover, and structural skin repair. Most brands buffer for comfort. We preserve for performance. The result? True resurfacing, without the sting.

The Sensitivity Shield
Irritant-Free Chemistry™
Formulated for the most sensitive, reactive, and allergy-prone skin, this system avoids every known barrier disruptor. That means: no synthetic fragrance, no dyes, no essential oils, no drying alcohols, and no harsh preservatives.
Every exclusion is backed by research. Every inclusion is skin-compatible. This isn’t just clean—it’s biologically considerate.
What We Leave Out
We believe clean is not enough. Puriste is formulated without fillers or irritants—because for skin to transform, it first has to feel safe.
FORMULATED WITHOUT
Fragrance
Dyes
Essential oils
Drying alcohols
Harsh preservatives
Silicones
PEGs
Microplastics

You’ve tried everything. Now try the one that works.
This is where it ends—the excess, the guessing, the overdoing. One night cream. One calibrated dose.Formulated by a dermatologist to replenish your skin.