
One Dose. One Step. At Night.
A single cream that does more—without anything unnecessary

Dermatologically Refined
Rooted in the dermatology practice of Dr. Garnis-Jones. Designed to renew, not overwhelm.
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The Science Behind Puriste
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CAG-pH4™
CAG-pH4™, a glycolic complex calibrated to a pH of 4.0—clinically shown to stimulate collagen production and accelerate cellular renewal.
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The Single-Dose Barrier System™
The Single-Dose Barrier System™, inspired by the precision of dermatological prescriptions—delivering one effective dose, supported by barrier-repairing lipids.
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Irritant-Free Chemistry
Irritant-Free Chemistry formulated to calm—not challenge—even the most sensitive skin.
Let customers speak for us
from 132 reviews"My skin has always been very reactive to skincare products. I literally tried every "dermatologist recommended" product you can find at a drugstore with no luck. As a result, I came to Dr. Garnis-Jones for a skin allergy test. After I received my results, she recommended her cream that was completely free of any of the allergens we discovered on the test, which was shockingly untrue for most other products I had tried. I thought there was no way my skin would tolerate an 8% glycolic acid, but it did and it even cleared some of the red scaling patches around my eyebrows. It feels like medicine for your skin!
“My dermatologist warned me my skin barrier was wrecked. After I took a break from skincare, I started using this once every other night and am shocked that it continues to be the only skincare I need aside from my daily lotion or sunscreen.
“I blew money on TikTok recs that wrecked my face. This cream healed my breakouts without wrecking my barrier. I will die on this hill.”
“I’ve worked in skincare clinics. I’ve seen trends come and go. But the fact that a dermatologist developed this for her own patients is everything. It’s not a celebrity collab or a marketing gimmick. It’s real, clinical, and it works.”
“This feels like medicine for your face. Not in a harsh, clinical way — in a finally-something-that-works way. My skin looks healthier, not just better.”
“This cream is the only one I’ve ever used that didn’t make my acne worse. It actually helped. I could feel it the moment I put it on and felt the light tingling from the glycolic acid. After a light purge and a bit of flaking, my skin is just clear and hydrated. It feels like skin rehab in a jar.”
“My skin flares up with everything — even ‘clean’ products. This cream calmed the redness and made me smoother. That combo is rare.”
“My derm said my pH was off. I used this cream for 3 weeks — now my oil is under control and my acne cleared. I literally don’t wear foundation anymore.”
“I first got this cream from Dr. Garnis-Jones in Ontario 15 years ago. I’ve tried to switch to other brands and every single time I come back. This is the only one that makes my skin feel safe.”
"I'm obsessed with how this product makes my skin tingle when I first apply it. It is such a relief to find something that you can feel is really working. It makes me feel like we have been lied to by other skincare companies for so long."
“Didn’t think skincare was for me until this cream erased ten years of dullness. I wish I had known about it sooner”
“I'm Filipina and have always struggled with dullness and pigment spots. This cream gave me a luminous look I thought only filters could do.”
“If I had to sum up this product in one sentence, I would say It's like a skincare Swiss Army knife.”
“I hated skincare. Too complicated, too expensive. Then I discovered Puriste. One jar. Done. My skin looks better than it ever did with 5 steps.”
“This made my skin look like I sleep 9 hours, drink green juice, and meditate. I don’t. It’s the cream.”
Shop Our 8% Glycolic Night Cream Now
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Glass Over Plastic
Our products are contained in recyclable glass to minimize plastic waste reduce environmental impact.
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Cruelty-Free, Always
We never test on animals—because caring for skin should never come at the cost of compassion
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Formulated in Canada
Crafted in independent Canadian labs—not mass-produced overseas. Every formula is developed under the eye of Dr. Garnis-Jones.